Malegra Pro 100 mg should not be taken by individuals who are allergic to sildenafil or any of the inactive ingredients in the medication. It should also be used with caution in individuals with certain medical conditions, such as cardiovascular disease, uncontrolled hypertension, or liver or kidney impairment. Malegra Pro 100 mg should not be used concomitantly with nitrates or alpha-blockers, as this can lead to potentially dangerous drops in blood pressure.